Working principle of vacuum freeze dryer

Working principle of vacuum freeze dryer:

After starting the machine, put the material into the material box for freezing. The freezing process of the material, on the one hand, is that the vacuum system vacuumizes a part of the water; On the other hand, when the material is frozen, the water contained in some molecules is discharged to the surface of the material for freezing. After the freezing requirements are met, the material is heated and dried by the heating system, and the water contained in the material is carried to the freezing trap for freezing by vacuuming, so as to meet the freezing and drying requirements of the material.

Freeze-drying refers to the process of removing water or other solvents from frozen biological products through sublimation. Sublimation refers to the process that a solvent, such as water, like dry ice, directly changes from solid to gas without going through liquid. The product obtained by freeze-drying is called lyophilization, and this process is called lyophilization. Traditional drying will cause material shrinkage and destroy cells. The structure of the sample will not be damaged during the freeze-drying process, because the solid components are supported by the solid ice at its position. When the ice sublimates, it will leave pores in the dry residual material. In this way, the integrity of biological and chemical structure and activity of the product is preserved. In the laboratory, lyophilization has many different uses. It is used in many biochemical and pharmaceutical applications. It is used to obtain biological materials that can be preserved for a long time, such as microbial culture, enzymes, blood, and drugs. In addition to the stability of long-term preservation, it also retains its inherent biological activity and structure. For this reason, lyophilization is used to prepare tissue samples for structural studies. Freeze-drying is also used in chemical analysis. It can obtain dry samples or concentrate samples to increase analytical sensitivity. Freeze-drying makes the composition of the sample stable without changing the chemical composition, and is an ideal auxiliary method for analysis. Freeze-drying can occur naturally. Under natural circumstances, this process is slow and unpredictable. Through the freeze drying system, people have improved and subdivided many steps to accelerate this process.